Increased Tenascin-C (TNC) protein expression in tumor tissue and CSF ...
Innovation: Diffuse intrinsic pontine glioma (DIPG) is the most deadly solid tumor in children, with rapid progression, poor response to therapy, and average survival less than one year from diagnosis. We describe a hypothesis-driven research plan to elucidate the mechanism by which Tenascin-C (TNC), an extracellular matrix (ECM) protein ...