Grant Search

Cancer Type

Keyword Search  

Categories

Grant Amount
>=

<=





Results: 160

Exploring Combination Therapy for DIPG: SGI-110 and GAA Vaccine

Diffuse intrinsic pontine glioma (DIPG) are some of the deadliest childhood brain tumors. The immune system protects the body by recognizing targets on harmful cells, but tumor cells can “switch off” the targets and hide from the immune system. We have been using a vaccine that can target ...

SARS-CoV-2 infection in brain cancer children: clinical characteristics and transmission ...

As at end of May 2020, Italy is one of the country’s most affected by COVID-19 worldwide, with ~230k cases and ~34k deaths attributed to the virus. The Milan area, being one of the epicenters of the Italian epidemic, is experiencing significant pressure on its health system, impacting the ...

Glycan Signatures of Resistance in Diffuse Intrinsic Pontine Glioma (DIPG)

Diffuse intrinsic pontine glioma (DIPG) is a brain tumor that primarily affects young children ages 5-9 and claims nearly all its victims in less than 2 years. DIPG tumors are located in the brainstem, rendering them inoperable, and radiation, the only FDA-approved treatment, inevitably results in recurrence as tumor cells develop ...

Repurposing antimalarial drugs for DIPG therapy

Diffuse intrinsic pontine gliomas (DIPGs) are rare but highly aggressive brain tumors found in the pons, an area of the brainstem that controls many of the body’s most vital functions such as breathing, blood pressure, and heart rate. Despite DIPG being the leading cause of pediatric death by ...

Pilot Trial to Evaluate the Feasibility and Clinical Utility of ...

Abstract: Outcomes in children with solid tumors that are already spread at the time of diagnosis or that do not respond with chemotherapy are generally poor and attempts to intensify treatment have not improved survival.  Personalized medicine is an emerging field of medicine that uses genetic information obtained from ...