Grant Search

Cancer Type

Keyword Search  

Categories

Grant Amount
>=

<=





Results: 138

Investigating the impact of radiation toxicity on immune response in ...

Abstract: Cancer is a disease caused by changes in the genes and a leading cause of death worldwide. Cancer treatment is challenging despite years of innovations and research. In advanced stage, it is largely incurable and poorer prognosis. Radiotherapy is one of the effective means of managing advanced stage ...

Diffuse Intrinsic Pontine Glioma.

In tumors like DIPG, the diagnosis itself spells a death sentence for the child affected. For several decades, none of the altered fractionation radiotherapy or additional chemotherapy or targeted agents have shown a significant benefit over conventional radiotherapy. We propose amalgamation of several known and tested hypothesis in DIPG ...

Interaction of Immune System with Oncolytic Measles Virus Therapy of ...

Medulloblastoma (MB) is the most common malignant brain tumor in children. The Group 3 MB patients have the worst prognosis and dismal 5-year survival rate among the four distinct subtypes of MB: WNT, SHH, Group 3 and Group 4 tumors. Sadly, MB survivors face life-long debilitating neurocognitive side effects from craniospinal radiation that ...

Photodynamic therapy of diffuse intrinsic pontine glioma in combination with ...

Diffuse intrinsic pontine glioma (DIPG) is a lethal childhood brain tumor and a leading cause of pediatric brain tumor-related mortality. Even with treatment, the median survival of patients with DIPG is 9–11 months. Despite a number of clinical trials, no treatments have proven more effective than radiation therapy (RT) for ...

Radionuclide therapy for somatostatin receptor-positive high-grade central nervous system tumors ...

Abstract: Brain and spine tumors are the leading cause of cancer-related death in children and adolescents. While cure can sometimes be achieved with conventional chemotherapy, surgery, and/or radiation, prognosis is dismal for patients whose aggressive brain/spine tumors progress despite these treatments. There is a critical need to develop ...